BiOpiniO Systems Biology develops Intranet-Solution for Neurodegenerative Diseases Research

(Recklinghausen, Germany) The combination of experimentally proven Protein-Protein Interactions with semi-manually extracted high-quality Pathway-Information from literature serves as unique hypothesis-platform for scientists.

BiOpiniO focusses on neurodegeneration. Sixty-five year old people have a 2-3% probability for developing Alzheimers’s disease and a 25-50% risk for people older than 85 years. The risk doubles every 5 years beginning with 65. With our increased expectancy of life these diseases will increase, too.

"Pure Proteomics-data do not explain any interrelationships, only with the very time-consuming comparison of what is already known with new scientific results enables the examination of the underlying principles and gives rise to new insights for the disease. Our databases shorten the analysis drastically by maintaining the highest quality”, explains Thomas Wiebringhaus of BiOpiniO. „The NIDE Portal is developed together with Prof. Dr. Klose from the Institute of Human Genetics (Charité, Berlin), thus we can combine our know-how and optimize the value for the researchers at the same time. The NIDE concept and the knowledge databases are also offered to other companies and research institutes, there is big interest in this.“

"BiOpiniO understood at once what we wanted. The generation and the characterization of the mouse models and the experiments took many years, with the prospects of Systems Biology we have now comprehensive analysis at hand which will hopefully give new insights for neurodegenerative diseases—we can now focus on the few really interesting targets.“ said Prof. Joachim Klose.
„BiOpiniO examines disease modifications on the level of networks to deliver new ideas for the development of new therapies. For this purpose high-value knowledge databases from BiOpiniO are applied."

"Scientists need a custom-tailored analysis platform that involves expert knowledge and combines it with the established knowledge from literature", explains Thomas Wiebringhaus of BiOpiniO. "The IDE fulfils exactly the needs of the scientists."
http://www.biopinio.com